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KMID : 0360319920240010092
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Journal of Korean Cancer Research Association
1992 Volume.24 No. 1 p.92 ~ p.101
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Malignant Lymphomas in Korea
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김홍태
임영혁/서창인/박영석/강원기/허대석/방영주/박선양/김병국
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Abstract
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It has been known that there are considerable geographic and ethnic differences in the incidence, age distribution, and histologic subtypes of lymphoma.
We studied the clinical characteristics of 500 patients with malignant lymphomas newly diagnosed at Seoul National University Hospital from Jan. 1978 to Dec. 1987. Hodgkin's disease was uncommon and accounted for 11.4% of all lymphomas.
The most common type of non-Hodgkin's lymphomas was diffuse histiocytic lymphoma of Rappaport(54.6%) and nodular lymphoma was very rare(4.5%).
In Hodgkin's disease, mixed cellularity type was most common(49.1%) and nodular sclerosis type was rare(8.8%). High proportion of lymphomas(about 1/2 of all lymphomas) were originated from the extranodal sites.
Among non-Hodgkin's lymphomas, we observed the difference in survival duration between low grade and intermediate grade group(P<0.05).
According to multivariate analysis using Cox regression hazard, stage and liver involvement were the most useful prognostic factors predicting survival in diffuse histiocytic lymphoma patients.
In conclusion, the characteristics of malignant lymphomas in Korea differ form those in the western countries but are similar to those in China and Japan.
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KEYWORD
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